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In this page, we will bring Key Studies on RF Radiation biological and health effects, and also epidemiological studies about the link to cancer.

Key Studies on RF EMF
Key Studies on RF-EMF

More and more studies show biological damage and health effects of RF EMR, even at very low levels which don’t cause any heat effect and were considered to be safe. Below are some key studies on the influence, changes, biological damage and possible health risk that made a mark on the discussion of whether EMF is a health risk or not.

Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucose Metabolism – Nora D. Volkow, MD 2011

“In healthy participants and compared with no exposure, 50-minute cell phone exposure was associated with increased brain glucose metabolism in the region closest to the antenna. This finding is of unknown clinical significance.”
The study – http://jama.jamanetwork.com/article.aspx?articleid=645813
JAMA. 2011;305(8):808-813. doi:10.1001/jama.2011.186

The outcomes of Volkov’s study were repeated in a study on LTE, from China “The alteration of spontaneous low-frequency oscillations caused by acute electromagnetic fields exposure – 2013” – “The study provided the evidence that 30min LTE RF-EMF exposure modulated the spontaneous low-frequency fluctuations in some brain regions.”

Link – http://www.ncbi.nlm.nih.gov/pubmed/24012322
About the study – http://www.prlog.org/12215083-lte-cell-phone-radiation-affects-brain-activity-in-cell-phone-users.html
PMID: 24012322 DOI: 10.1016/j.clinph.2013.07.018

Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucose Metabolism - Nora D. Volkow,
Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucose Metabolism – Nora D. Volkow,

Brain damage after RF-MW exposure – Salford -2003

The picture below is taken from the “Nerve Cell Damage in Mammalian Brain after Exposure to Microwaves from GSM Mobile Phones” study by Leif G. Salford, Arne E. Brun, Jacob L. Eberhardt, Lars Malmgren, Bertil R.R. Persson. (please see the source link below for full study).
Please notice the red spots on the radiated brain (Right picture), these are “protein leakage from blood vessels” marking the damage to the brain’s blood vessels which can cause headaches and other symptoms.
Source: http://www.ncbi.nlm.nih.gov/pubmed/12782486
Full study: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241519/pdf/ehp0111-000881.pdf
Video of a lecture with Dr. Leif Salford: http://youtu.be/E_WJ_aJPWIA 
PMID: 12782486 PMCID: PMC1241519 DOI: 10.1289/ehp.6039

Brain damage after RF-MW exposure - Salford -2003
Brain damage after RF-MW exposure – Salford -2003

DNA brakes – Henry Lai and Dr. Narendra -1996

The comet trail “dust-like” particles in the pictures are DNA breaks. The picture below clearly shows that DNA breaks accusers after exposure to X-ray and Cell phone radiation. The source of the picture is from Dr. Henry Lai and Dr. Narendra research about “Single- and double-strand DNA breaks in rat brain cells after acute exposure to radio-frequency electromagnetic radiation”

DNA brakes - Henry Lai and Dr Narendra -1996
DNA brakes – Henry Lai and Dr. Narendra -1996

Source:  http://www.ncbi.nlm.nih.gov/pubmed/8627134

Dr. Neil Cherry about Motorola attempt to contradict this study

Dr. Neil Cherry wrote a number of papers regarding the danger of RF radiation. One was specific about the studies that Motorola founded in order to allegedly contradict Henry Lai studies. The paper used to be available on this link, but it seems to be removed. The info also appears on other papers of Neil Cherry. Click on the links below and search for “Motorola”:

  1. Evidence of Health Effects of Electromagnetic Radiation, To the Australian Senate Inquiry into Electromagnetic Radiation – Dr. Neil Cherry  
  2. Evidence that Electromagnetic Radiation is Genotoxic: The implications for the epidemiology of cancer and cardiac, neurological and reproductive effects  – Dr. Neil Cherry  

Video of a lecture given by Dr. Henry Lai about DNA breaks as an outcome of RF exposure: http://youtu.be/JrBjQJhHfzk

Creation of Free radicals as a result of RF radiation exposure – Friedman J- 2007

On their research Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies from 2007, Dr. Joseph Friedman and Prof. Roni Seger, from the Department of Biological Regulation, The Weizmann Institute of Science (in Israel), found that exposure to RF electromagnetic radiation caused oxygenate stress and for the first time showed a detailed molecular mechanism by which electromagnetic radiation from mobile phones interacts and changes cell communication and activities.

Creation of Free radicals as a result of RF radiation exposure - Friedman J- 2007
Creation of Free radicals as a result of RF radiation exposure – Friedman J- 2007

The Interphone Study 2011

27 minutes of cellphone use per day increase brain cancer risk  – The Interphone study – 2010 

The Interphone study final result ware published on 17/05/2010, after 5 years of delay. a first look suggests that using a mobile phone actually protect you from brain cancer, how could that be? a second look shows that people who use their mobile phone for more than 27 minutes per day (1640 hours in 10 years) have a 40% higher risk of getting a brain tumor. In the study itself, there were many issues and problems that cause the results to be moderated. Appendix 2 of the study tries to mathematically fix some of the problems in the study resulting in higher risk (please see picture below).

Abstract – https://www.ncbi.nlm.nih.gov/pubmed/20483835
Interphone study formal report: http://ije.oxfordjournals.org/content/39/3/675.full.pdf

Appendix 1 – http://ije.oxfordjournals.org/content/suppl/2010/05/06/dyq079.DC1/Interphone_Appendix1.pdf
Link – https://drive.google.com/file/d/1IeZcNmnE-WfywjX6cHWxRKqIlHB4qVo_/view?usp=sharing

Appendix 2 – http://ije.oxfordjournals.org/content/suppl/2010/05/06/dyq079.DC1/Interphone_Appendix2.pdf
Link – https://drive.google.com/file/d/1_E648J4WQOBV9R1r4j1mLqt4tpBeW12q/view?usp=sharing

About the interphone study: http://norad4u.blogspot.com/2010/05/what-went-wrong-with-interphone-study.html
PMID: 20483835 DOI: 10.1093/ije/dyq079

Table 2 (out of the Interphone study) - ORs between mobile phone use and brain tumors (meningioma and glioma separately).
Table 2 (out of the Interphone study) – ORs between mobile phone use and brain tumors (meningioma and glioma separately).
Table 2 (out of the appendix # 2 of the Interphone study) - ORs is higher!
Table 2 (out of the appendix # 2 of the Interphone study) – ORs is higher!

The NTP Study

a US$25,000,000 study done by the NTP (National Toxicology Program, USA) that was built to test if the long-held assumption that the only health effect of low-level RF radiation is some heat.

Study found:
More Glioma in rodents that were exposed to RFR (Radio Frequency Radiation)
More Swanova of the hart in rodents that were exposed to RFR
More Precancerous conditions in rodents that were exposed to RFR
More DNA break in rodents that were exposed to RFR
Smaller offsprings to  rodents that were exposed to RFR

Findings of the NTS study from the fact sheet
Findings of the NTS study from the fact sheet
NTP study bottom line
NTP study bottom line – the long-held assumption is not valid

Press conference – 
https://www.niehs.nih.gov/news/newsroom/releases/2018/november1/index.cfm
Summary of the study – https://ntp.niehs.nih.gov/results/areas/cellphones/
List of studies within the NTP project – https://ntp.niehs.nih.gov/testing/status/agents/ts-08013.html
Rats final – Final Rat Study Report – https://www.niehs.nih.gov/ntp-temp/tr595_508.pdf
Mice Final – Final Mouse Study Report – https://www.niehs.nih.gov/ntp-temp/tr596_508.pdf
Face Sheet – https://www.niehs.nih.gov/health/materials/cell_phone_radiofrequency_radiation_studies_508.pdf

DNA article of this study, preliminary published at 10-2019 – https://onlinelibrary.wiley.com/doi/abs/10.1002/em.22343?

Cellphone and cordless phones use and brain cancer – Lennart Hardell – 2010

“Use of mobile phones has an increased risk, highest in the >10 years’ latency group yielding odds ratio (OR) = 2.4, and 95% confidence interval (CI) = 1.4-4.1. The risk increased with a cumulative number of lifetime hours for use, and was highest in the >2,000 h group (OR = 3.4, 95% CI = 1.6-7.1).”
Lennart Hardell is a world-known scientist in the field of electromagnetic radiation. His many studies and reviews show a constant correlation between RF exposure and health effects.
Link to this study:http://www.ncbi.nlm.nih.gov/pubmed/20551697
PMID: 20551697 DOI: 10.1159/000311044
Link to other publications by Hardell: http://www.ncbi.nlm.nih.gov/pubmed?term=%22Hardell%20L%22%5BAuthor%5D
Link to an additional study about RF from home devices by Hardel – https://www.ncbi.nlm.nih.gov/pubmed/20551697


Polish army RF-MW exposure study – Szmigielski S – 1996   

“Cancer morbidity in subjects occupationally exposed to high frequency (radiofrequency and microwave) electromagnetic radiation”. this study tracked the RF-MW exposure levels and health records of army personnel of the polish army for 15 years (both soldiers that were exposed and those who were not). The study shows that a person that was exposed to RF-WM radiation had an added-risk of 2.07 of cancer and that their morbidity rate was higher.
Link to the study: http://www.ncbi.nlm.nih.gov/pubmed/8717316
About the study: http://www.microwavenews.com/news/backissues/m-j95issue.pdf
PMID: 8717316 DOI: 10.1016/0048-9697(95)04915-0

Lymphoma cancer in mice – Repacholi MH -1997

Mike Repacholi, the former head of ICNIRP (1995-2005), former head of WHO EMF PROJECT (1995-2005) and his students exposed mice to RF radiation, similar to that emitted from cell phones, and found that the risk for Lymphoma was found to be significantly higher in the mice that were exposed (OR=2.5). This study was published in 1997. Several years after the research was done, Repacholi took back his findings and criticized the students for the publication of the study. After leaving his roles in WHO and ICNIRP he was appointed as an industry consultant, regarding the ways to handle the public fear from EMF.
The research: http://www.ncbi.nlm.nih.gov/pubmed/9146709
PMID: 9146709

Cell phone usage by pregnant women and of children causes behavioral difficulties – Divan HAKheifets LObel COlsen J – 2008

“Exposure to cell phones prenatally-and, to a lesser degree, postnatal-was associated with behavioral difficulties such as emotional and hyperactivity problems around the age of school entry”
Link to the study: http://www.ncbi.nlm.nih.gov/pubmed/18467962


More studies from Israel

Since I am from Israel, I would like to add several studies from local researches, other than the ERK study by Roni Zeger and Yossi Friedman (please see above).

2 Studies by Korenstein R 2003

Terahertz radiation increases genomic instability in human lymphocyteshttps://www.ncbi.nlm.nih.gov/pubmed/18666810
PMID: 18666810 DOI: 10.1667/RR0944.1
” continuous-wave (CW) 0.1 THz radiation (0.031 mW/ cm(2)) to dividing lymphocytes for 1, 2 and 24 h and examined the changes in chromosome number of chromosomes 1, 10, 11 and 17 and changes in the replication timing of their centromeres using interphase fluorescence in situ hybridization (FISH) “


Exposure of human peripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chromosomal instability. – http://www.ncbi.nlm.nih.gov/pubmed/12524674
PMID: 12524674 DOI: 10.1002/bem.10086
” in vitro exposure of human peripheral blood lymphocytes (PBL) to continuous 830 MHz electromagnetic fields causes losses and gains of chromosomes (aneuploidy), a major “somatic mutation” leading to genomic instability and thereby to cancer. ”
Exposure level 1.6-8.8W/Kg over 72 hours.
Temp 34.5-37.5 degrees C.

slide from Korenstein R presentation
Screenshot of a slide from Korenstein R presentation

Non-Thermal Electromagnetic Radiation Damage to Lens Epithelium – Dovrat, Levi Schächter – 2008

” Exposure to 1.1 GHz, 2.22 mW microwaves caused a reversible decrease in lens optical quality accompanied by irreversible morphological and biochemical damage to the lens epithelial cell layer. The effect of the electromagnetic radiation on the lens epithelium was remarkably different from those of conductive heat.  “
Link – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694600/
doi: 10.2174/1874364100802010102

On the upper left, a normal lens.  On the lower left, a heat damage on the lens. On the right, RF damage on the lens. The screen shot out of  Levi Schächter  presentation
On the upper left, a normal lens.
On the lower left, heat damage on the lens.
On the right, RF damage on the lens.
The screenshot out of Levi Schächter presentation

Increased incidence of cancer near a cellphone transmitter station – Ronni & Danny Wolf

This study published by 2 Israeli MD, in the  International Journal of cancer prevention in January 2004, showed more incidence of cancer near cell towers, in comparison to the overall population.
Link – https://docs.google.com/viewer?a=v&pid=sites&srcid=ZGVmYXVsdGRvbWFpbnxjZWxsdWxhcnNoYWZ1aXxneDoyOTY4ZTZiNjY1NTI1Y2Fm
or
https://www.researchgate.net/publication/228490892_Increased_incidence_of_cancer_near_a_cell-phone_transmitter_station

More studies about RF radiation biological and health effects